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GLP-1s work to manage blood sugar levels by promoting insulin release only when blood glucose is elevated
This is particularly important when switching from a GLP-1 based therapy to non-GLP-1 options, because the metabolic adjustment can affect blood sugar regulation, blood pressure, and heart rate in ways that warrant monitoring
What happens with extended use over months or years is unknown territory
Kroenke K, Spitzer RL, Williams JBW (2001) The PHQ-9
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