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[25] A human prospective cohort study conducted on a sample of 266 people over age 60 demonstrated that treatment with epithalamin, the pineal gland extract upon which epitalon is based, produced a 1 } : CS1 maint: deprecated archival service (link) al
Thus, as demonstrated with in vitro experiments, norepinephrine binds and activates D 4 Rs at submicromolar concentrations (35, 4446), up to ten times higher than the concentration able to activate 1 R or 1B R in pineal cell preparations or pineal tissue (47, 48)
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