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If metoclopramide is used, clinicians should be aware of its FDA boxed warning regarding tardive dyskinesia with long-term use and limit duration of therapy

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Based on evidence from 12 population-based studies across 10 European countries, the reported prevalence of HAE-C1-INH (Type 1/2) ranged from 0.05/10,000 individuals in Latvia to 0.33/10,000 in Austria

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