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The main practical disadvantages are: poor absorption in standard capsule form, the need for consistent daily use over 8-12+ weeks before visible results, relatively higher cost for well-absorbed formats, mild and uncommon side effects like digestive discomfort or headache in some users, and the risk of unrealistic expectations from aggressive marketing claims
Expect a wide range
These are fundamentally different from a probiotic approach
The failure of the Exenatide-PD3 and NLY01 trials has cast serious doubt on whether GLP-1 RAs have a future in PD
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