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doi: 10.3945/ajcn.114.086918 Summary Keywords nutritional interventions, osteoarthritis, metabolism, inflammation, oxidative stress, gut-joint axis Citation Wang Y, Cao Z, Gao Y, Shao P, Gao S, Dong M, Tian Z, Feng Y, Xu J and Xiang C (2025) Nutritional interventions for osteoarthritis: targeting the metabolism-inflammation-oxidative stress axisclinical evidence and translational practice
Depending on the situation, evaluation may include discussion of labs, inflammation, metabolic health, hormone balance, sleep, nutrient status, physical therapy, medication effects, or referral when appropriate
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Together, these findings underscore that NSW alters estrogenic activity in women, primarily through elevated estradiol in certain populations, with stronger effects in postmenopausal women and modulation by chronotype and circadian disruption 251
