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Melatonin reprograms the effector state of activated ILC2s To further dissect the effects we had observed, we isolated aILC2s from IL-33 challenged BALB/c mice ( Supplementary Figures 2 ) and performed bulk RNA sequencing, comparing the transcriptome of vehicle and melatonin treated cells ( Figure 5A )

The available evidence is preclinical and comes from cell and animal research

[PMC free article] [PubMed] [CrossRef] [Google Scholar] Fulghesu AM, Ciampelli M, Muzj G, Belosi C, Selvaggi L, Ayala GF, Lanzone A

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