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Dermauw W, Wybouw N, Rombauts S, Menten B, Vontas J, Grbic M
Gasdermins can be cleaved and activated by a diverse array of other proteases in addition to caspase-1, including hematopoietic cell proteases (for example, granzymes, neutrophil elastase and cathepsin G) 17 and bacterial virulence factors (for example, SpeB) 18
GOT2 catalyzes the conversion of oxaloacetate to aspartate in the mitochondria and has been shown to be an important regulator of cancer metabolism (13)
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