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Serious adverse effects are rarely reported, though the absence of large-scale human clinical trials means some uncertainty remains about long-term safety
Home Care Tips to Prevent Melasma from Coming Back Apply Sunscreen Daily: Sun exposure is the main cause of melasma returning, so apply a broad-spectrum SPF 3050 daily, even indoors
Those with a history of severe allergies While allergic reactions are rare, people with past reactions to IV treatments, medications, or supplements may face a higher risk
Cleanliness: Always use sterile techniques to minimize the risk of infection
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