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The clinical implication: starting a patient on a medication they cannot afford for 6-12 months creates a predictable failure mode
Which means that even if theres a successful trial, it likely wouldnt be until 2027 or later that its vaccine hits the market
At present, four pathways for drug loading into cells can be considered: (i) non-covalent binding, (ii) covalent binding to cell membrane, (iii) internalization via cell endocytosis, and (iv) specific antibody-antigen interactions [211]
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