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Supplementation may be useful in selected circumstances, but it remains one part of a much larger biological system
Rarely, and almost exclusively from injections rather than oral supplements
In HD, a Phase II trial (NCT00608881) was terminated early due to futility, as CoQ10 failed to slow functional decline or improve survival, with a slightly higher, though not statistically significant, mortality rate observed in the treatment group (McGarry et al., 2017)
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