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The weight loss trap When readers ask us about vitamin B12 injection dosage and frequency for weight loss, we give the same answer every time: this is not a legitimate reason to take B12 shots

Prescriptions, particularly for controlled substances, may require an in-person evaluation depending on the state of residence and current federal regulations

Mechanistically they do not overlap (GLP-1 agonists work through appetite and gastric emptying, this works on adipocyte lipogenesis and NAD+), and the mouse data specifically showed fat loss without reduced food intake, so they are not redundant

Some people may struggle to absorb enough through food or supplements, making injections a helpful option