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Targeting ETC CI enhances 5FU response and extends survival The ultimate goal of better understanding mechanisms promoting 5FU tolerance is to allow us to design rational treatment combinations that are more effective than the current standard of care
Typically, these openings leave no visible scarring after they heal
Unlike conventional DAT blockers such as methylphenidate, the disruption of D2R-DAT leads to decreased membrane expression of DAT, while leaves the remaining DAT functional to facilitate the reuptake of dopamine [23]
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