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Myc has been shown to form a complex with Nrf2, inhibit Nrf2 binding to the ARE promoter region, and shorten the half-life of Nrf2 ( In a cluster analysis of 100 patients with pulmonary MAC disease, a distinct group (C2) was identified in addition to two groups (C1, C3), which resembled the experimental results observed in mice

Therefore, Billings LK, et al

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Human dosing, long-term safety, and drug interactions are not established

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