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If necessary, patients may transition to a more potent medication or explore whether surgical options could provide longer-term stability
During the study period, there were 27 major adverse cardiovascular events, including heart attack and stroke, among people who received retatrutide, compared with 23 events in the placebo group
Suppression of glutamatergic synaptic transmission may be associated with the reduced excitability of GLP-1R activation (Ong et al., 2017)
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