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In parallel, it alters transcriptional pathways involved in angiogenesis, cytokine production, and tissue remodeling, including PI3K/Akt and NF-B cascades
In the central nervous system, the action of GLP-1 and GLP-1RAs on its receptors can affect a variety of brain functions including satiety, thermogenesis, influence blood pressure, neurogenesis, neurodegeneration, retinal repair, and change energy homeostasis [16-20]
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