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THERAPEUTIC APPROACHES FOR MAINTAINING -CELL MASS IN PATIENTS WITH DIABETES Mode of action Animal studies Human studies Mode of action Animal studies Human studies DPP-4 and mode of action of its inhibitors Animal studies Human studies Role of GSK3 in diabetes and mode of action of its inhibitors Animal studies Role of GPR40 in diabetes and mode of action of agonists In vitro studies In vivo studies The treatment of patients with T2DM should aim not only to control glucose levels, but also to prevent the gradual decline in -cell function and decrease in -cell mass
Link: CNBC How Ozempic and Wegovy turned Novo Nordisk into a $400 billion company? (October 11, 2023)
Diabetes Care 44 , 10201026 (2021)
Over 26 weeks, tesamorelin reduced visceral adipose tissue by a mean of 34 square centimeters compared to an increase of 8 square centimeters in the placebo group
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