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Back in 1980, studies indicated that SystemX c was capable of transferring cystine into cells and simultaneously exchanging glutamate at a ratio of 1:1 in an ATP-independent manner (Bannai and Kitamura, 1980
Is it enough to use on its own
(2017) MYC-driven inhibition of the glutamate-cysteine ligase promotes glutathione depletion in liver cancer, EMBO Rep
doi:10.1074/jbc.M510764200
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