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The chronic subcutaneous administration of Ex-4 attenuates the peripheral symptoms of type 2 diabetes in rats, including hyperglycemia and IR, and enhances the levels of brain cortical GLP-1 and insulin-like growth factor (IGF)-1 and their downstream signaling pathways
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Compared with the HCD group, the HCD + ALC group exhibited significantly decreased hepatic protein levels of SREBP2 (Figure 3B), 3-hydroxy-3-methyl-glutaryl-CoA reductase (HMGCR
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