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C., Taylor, D

Not everyone benefits from split dosing, and single morning administration works well for many users

A study by Wegman et al

Environmental chemical-induced intestinal microbiome alternations might lead to systemic effects in the host ( TCE exposure, which is known to induce/exacerbate SLE in both experimental animals and humans, is also reported to cause alterations in the gut microbiome with increased abundance of genus Bifidobacterium and bacterial family Enterobacteriaceae as well as lower abundance of the genus Bacteroides and Lactobacillus in MRL+/+ mice at a high but occupationally relevant TCE dose compared to controls (105)