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Compounded versions are typically 6085% less expensive and are legally available when the FDA has confirmed a shortage of the branded product, which has been ongoing for tirzepatide since 2024
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Exendin-4, which shows 53% structural homology with GLP-1 (7-36), is as potent as endogenous GLP-1 in its insulinotropic effects via the mammalian GLP-1R
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