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Despite causing an increased susceptibility to OS, G6PD deficiency may also protect against CVD, since NADPH is an essential cofactor for enzyme 3-hydroxy-3-methylglutaryl-coenzyme A reductase (HMG-CoA R), and G6PD deficiency or NADPH deficiency may restrain HMG-CoA R activity similarly to statins (Fig
Moreno-Garca J, Garca-Martnez T, Moreno J, Mauricio JC (2015a) Proteins involved in flor yeast carbon metabolism under biofilm formation conditions
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This fits in with the triggers we saw above from England's Health System review
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