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FIDELIO-DKD was a phase 3 trial of finerenone, in addition to standard of care, in participants with T2DM, moderately advanced CKD (mean baseline eGFR was 44 mL/min/1.73 m 2 with a median UACR of 852 mg/g) with the majority (87%) having macroalbuminuria [100]
Immunohistochemistry As this study aimed to investigate the long-term impact of maternal SE and L-Carnitine supplement on the offspring, the brains from the offspring at 13 weeks, representing adulthood, were accessed for apoptosis and DNA damage
doi: 10.1016/j.bbrc.2012.09.104 44 LalloyerF.MogilenkoD
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