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In addition, DPP-4 cleaved GLP-1(7-36)amide and GLP-1(7-37) to form GLP-1(9-36)amide or GLP-1(9-37), low-affinity ligand of GLP-1 receptor and nonprimary role in regulating glucose metabolism (98101)

Peters says the industry is still understanding some of the potential risks of these medications, and it will be important to identify who may be at greater risk for those issues