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The many benefits that DARPins possess make them the perfect scaffold for the development of protein drugs, including high thermal stability, with denaturation midpoints from 66 to 95 C, and high solubility in solution, up to 100 mg/mL 30,50
Healthcare professionals managing such patients should document the rationale for both medications, monitor for adverse effects, and regularly review the necessity of continuing both treatments
By combining deep regulatory knowledge with practical industry insight, we provide tailored guidance that helps clients reduce risk, protect their brands, and conduct their business with clarity and confidence in this highly regulated and changing environment
Recent developments include Roche's acquisition of Carmot Therapeutics for dual GLP-1/GIP assets, Novo Nordisk's oral semaglutide approval, and Pfizer's USD 2 billion deal
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