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Bupleurum comprises saponins, flavonoids, monoterpene glycosides, as well as coumarins and lignins as its chemical constituents
IGF-1 promotes keratinocyte migration, wound epithelialization, and hyaluronan synthesis, aiding in challenging wound recovery, such as burns and diabetic ulcers (10)
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Further evidence is needed to understand its role in renal hemodynamics, fibrosis, cell damage and atherosclerosis, as well as to conclusively show reduction of hard renal outcomes
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