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Future studies should aim to clarify the pharmacokinetic and pharmacodynamic mechanisms underpinning their interaction, with an emphasis on identifying specific patient populations that may be at increased risk
Underlying factors : Identifying medical conditions (such as insulin resistance or type 2 diabetes) that might influence treatment decisions
Patients with pre-existing kidney disease should exercise particular caution and discuss magnesium supplementation with their healthcare provider before starting, as impaired renal function reduces magnesium excretion and can lead to hypermagnesaemia (elevated magnesium levels)
These can include nausea, diarrhea, constipation, or stomach discomfort, especially in the initial stages of treatment
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