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For example, GLP-1R in adipocytes can directly regulate apoptosis and preadipocyte proliferation by activating the adenylate cyclase/cyclic adenosine monophosphate (AC/cAMP) signaling pathway and various cell signaling cascades, including extracellular signal-regulated kinase (ERK), protein kinase C (PKC), and protein kinase B (AKT) [41,46]

A single molecule, Mounjaro is a once-weekly glucose-dependent insulinotropic polypeptide (GIP) and glucagon-like peptide-1 (GLP-1) receptor agonist

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