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Oxidative stress is caused by an overproduction of oxidants or unbalanced defence mechanisms played by antioxidants and their related enzymes
A Cochrane systematic review of NAC for COPD exacerbations (39 RCTs, n=7,436) found that NAC and other mucolytics significantly reduced the frequency of acute exacerbations (OR 0.75, 95% CI 0.62-0.92) (Poole et al., Cochrane Database Syst Rev, 2019) [43]
Retrieved 4 November 2017
Long-term use of PPIs can lead to Vitamin B12 deficiency. PPIs cut down on stomach acid, which is needed to release Vitamin B12 from food proteins
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