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10.1016/j.anireprosci.2007.07.009 61
"Delaying the mitochondrial decay of aging with acetylcarnitine." Annals of the New York Academy of Sciences
User reports commonly describe improvements in bloating, digestive discomfort, and bowel regularity within 1 to 2 weeks, with full therapeutic benefit emerging over 4 to 6 weeks
It is synthesised in the cytosol by glutamate-cysteine ligase (EC 6.3.2.2) and glutathione synthetase, with the first, rate-limiting step feedback-inhibited by glutathione itself and intracellular concentrations typically 1 to 8 mM (Griffith, Free Radical Biology and Medicine, 1999)
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