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Tirzepatide functions as a dual-action GLP-1 and GIP receptor agonist, which helps to regulate appetite and glucose levels
A recent US landmark study had calculated the incremental cost-effectiveness ratios of Trizepatide and Semaglutide to be $197 023 (US dollars) /quality adjusted life years and $467 676 (US dollars) /quality adjusted life years, respectively
In the clinical Phase I study, the most common reported side effects at a dose of 0.025 mg/kg were: nausea (classified as severe in 12.9% of subjects), yawning, facial flushing, and transient fatigue Dorr et al., 199600160-3)
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