PMID: 29155147): 5-Amino-1MQ showed NNMT selectivity with IC50 of 1.2 microM Reduced body weight and white adipose mass in diet-induced obese mice over 11 days No effect on food intake, suggesting metabolic rather than appetitive mechanism Nicotinamide N-methyltransferase inhibition mimics and boosts exercise-mediated improvements in muscle function in aged mice , published in Scientific Reports (Dimet-Wiley AL et al., 2024
When combined with caloric restriction, they support an additional 2-4 pounds of weight loss per month compared to diet alone
Theyre essential for obtaining energy, regulating hormones, forming red blood cells, breaking down blood sugar, metabolizing food, growing skin, hair, and nails, and promoting cell growth
B12 books I found useful "What You Need to Know About Pernicious Anaemia and B12 Deficiency" by Martyn Hooper Martyn Hooper is the chair of PAS (Pernicious Anaemia Society)