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All participants received counseling on physical activity and a reduced-calorie diet The primary endpoints were percent change in body weight and the change in the Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC) pain score A key confirmatory secondary end point was the physical-function score on the 36-Item Short Form Health Survey (SF-36), version 2 Lets take a moment and talk about these scales

43 Currently, these drugs are primarily in the development and clinical trial stages, but preliminary research results have shown their potential powerful effects in reducing blood sugar and body weight

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