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340 Tri-Agonist for GLP-1R, GIPR and GCGR Recently, a triple agonist for GLP-1R, GIPR and GCGR was developed and tested on diet-induced obese mice

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Ab#2_DBS#1 has a reduced GLP-1R potency compared to the parent fusion but to a lesser extent than the glycosylated Ab#2_GLP1 W25N V27S (5.3 and 30 nM respectively)