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Taking both together makes sense for most people, though folate status should be adequate before starting high-dose b12 to avoid masking folate deficiency

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But the AOD 9604 and tirzepatide stack attacks the problem from two entirely different directions, creating what some clinicians describe as a synergistic metabolic advantage that neither compound achieves alone

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The intramuscular method helps B12 absorb slowly

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They also need to adjust the schedule of treatments

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