Alcohol abuse can lead to vitamin B12 deficiency due to the following reasons: Alcohol consumption can reduce B-12 absorption as chronic alcohol consumption can lead to gastritis (inflammation of the stomach lining) and impair the production of intrinsic factor, which is a protein necessary for the absorption of vitamin B12
1,2,6 Neurologic manifestations are caused by progressive demyelination and can include peripheral neuropathy, areflexia, and the loss of proprioception and vibratory sense
Patients should discuss any supplement use with their prescribing clinician before combining products
Food Chem Toxicol 62:869875 Wen X, Huang A, Hu J, Zhong Z, Liu Y, Li Z, Pan X, Liu Z (2015) Neuroprotective effect of astaxanthin against glutamate-induced cytotoxicity in HT22 cells: involvement of the Akt/GSK-3 pathway