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Additionally, dysregulation of the kynurenine metabolism pathway has also been observed in BD patients, characterized by increased tryptophan degradation, along with elevated levels of kynurenine (KYN), kynurenic acid (KYNA), 3-hydroxyanthranilic acid (3HAA), 3-hydroxykynurenine (3HK), and quinolinic acid (QUIN) in serum