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Furthermore, Cornu and colleagues found an autocrine loop where GLP-1 prevents the death of -cells in an IGF-1R-dependent manner via secretion of IGF-2 from the same cells (39)

Overall prescribing trends The study found that 1,449,442 patients were prescribed a GLP-1 RA between January 2018 and September 2024, with 6,341,367 total prescriptions during this period

The team at IBI Wellness can help answer questions on semaglutide, how it works, and if you might be a candidate for GLP-1 medications