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When to Talk to Your Clinician Report large or spreading bruises, unexpected bleeding, persistent constipation that does not respond to: Basic measures Severe abdominal pain New muscle weakness Also discuss any routine medications that increase bleeding risk so your prescriber can adjust monitoring or dosing
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[1] [4] Treatment usually begins with a 0.25 mg weekly dose for 4 weeks (for tolerability), then increases to 0.5 mg weekly, with a maintenance dose of 0.5-1 mg weekly as determined by your healthcare professional
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