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Post hoc mediation analysis across SURPASS-1 through SURPASS-5 found that decreases in systolic blood pressure (ranging from 1.3 mmHg to 11.5 mmHg across the tirzepatide doses) were primarily mediated through weight loss [91]
Additional treatment options, dosage levels, and extended care programs may be available based on individual patient needs
GLP-1 (glucagon-like-peptide-1), a receptor agonist, which means that it mimics the hormone GLP-1 known for regulating hunger (and therefore food intake)
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