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Downstream tissue effects persist substantially longer
However, attempts to measure MTOB and homomethionine transport activity of recombinant BAT5 in vitro were not successful till now, as the direct measurements of transport of these substrates in artificial membranes is problematic due to higher hydrophobicity of substrates leading to unspecific membrane binding and permeation, which override the specific transport events (Gigolashvili et al., 2009)
Patients eventually reported hunger levels similar to those taking placebo
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