If you have risk factors: Family history of thyroid disease or autoimmune conditions, other autoimmune conditions (type 1 diabetes, celiac disease, rheumatoid arthritis), history of thyroid issues during or after pregnancy, unexplained infertility or recurrent miscarriage
The team examined the effect of this variant on different types of lean mass, including appendicular lean mass, whole body fat-free mass, and trunk fat-free mass, as well as various measures of body fat, such as whole-body fat mass, trunk fat mass, trunk fat percentage, body fat percentage, and waist-to-hip ratio
The effect is usually indirect, caused by fatigue from caloric restriction, GI discomfort, or hormonal shifts from rapid weight loss
That is a consistent pattern of failure to demonstrate the primary endpoint: significant fat reduction in humans