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Chen J, Wang W, Zhang T, Ji J, Qian Q, Lu L, Fu H, Jin W, Cui D
Interested in peptides
NNMT inhibition preserved nicotinamide substrate pool Reduced nicotinamide methylation conserved S-adenosyl methionine Elevated intracellular NAD+ increased sirtuin pathway activity Adipocyte metabolic shift altered lipid handling in cell models Core Areas of Scientific Investigation NNMT Enzyme Inhibition: NNMT activity is elevated in adipose tissue in obesity models
It was marketed under the brand name Byetta and got approval in 2005
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