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During lyophilization, peptides are frozen and exposed to controlled low-pressure conditions

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Biochem Biophys Res Commun (2009) 390(3):80914

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However, these are major surgeries and require thorough evaluation and lifelong commitment to lifestyle changes

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Stimuli with high incentive salience, such as hyperpalatable foods, capture attention, activate affective states, and motivate behaviors (Berridge, 2012)

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