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Raised intracellular NAD+ and SAM In cultured adipocytes, NNMT inhibition lowered 1-methylnicotinamide and raised both NAD+ and SAM, the biochemical signature researchers look for when the metabolic sink is blocked [1]

Its core physiological function is to catalyze the methylation of nicotinamide (NAM, a key precursor for NAD+ synthesis) with Sadenosylmethionine (SAM) to produce 1methylnicotinamide (1MNA)

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Most clients receive injections weekly to monthly, depending on their goals and lab results