Examples of FDA-approved peptides: Semaglutide (Ozempic, Wegovy): Approved for: Type 2 diabetes (Ozempic), obesity (Wegovy) Legal status: Prescription required, completely legal Schedule: Not a controlled substance Availability: Through licensed pharmacies with valid prescription Tirzepatide (Mounjaro, Zepbound): Approved for: Type 2 diabetes (Mounjaro), obesity (Zepbound) Legal status: Prescription required, completely legal Recent: Approved 2022-2023 Tesamorelin (Egrifta): Approved for: HIV-associated lipodystrophy (belly fat) Legal status: Prescription required, completely legal Sermorelin, CJC-1295 (with DAC - as Tesamorelin precursor): Some formulations approved for specific conditions Generally require prescription through compounding pharmacies PT-141 (Bremelanotide/Vyleesi): Approved for: Female sexual dysfunction Legal status: Prescription required, completely legal Key point: If a peptide is FDA-approved and you have a legitimate prescription, it's 100% legal

The break is not about tolerance, since neither peptide has a well described desensitization mechanism
It typically lasts 15-60 minutes after injection and occurs most frequently during the first few doses as your body adjusts
If a household refrigerator is the only option, use a thermometer, keep the vial boxed, and avoid locations that freeze