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Activation of UQCRC2-dependent mitophagy by tetramethylpyrazine inhibits MLKL-mediated hepatocyte necroptosis in alcoholic liver disease

Kidney function biomarkers including creatinine clearance and urea levels showed normalization toward younger reference values, indicating restoration of tissue homeostasis

GHK is a naturally occurring peptide found in human plasma and other body fluids

As the residue identity between MPGES1 and MGST1 is partly high for the TM1-TM2 loop (in this cytoplasmic loop, 5 out of 8 residues among K42-D49 are conserved between MGST1 and MPGES1), it may be the case also for MGST1 that this loop is not directly involved in GSH binding but serves other purposes