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You might wonder how a pill works if you lack intrinsic factor: at very high oral doses, a small amount of B12 can be absorbed directly through the gut wall via passive diffusion, bypassing the need for intrinsic factor entirely [1] [3]
1 Will the gastric-emptying effect last, or does it wear off
In smaller doses, also known as low dose naltrexone, the medication has some mechanisms of action that have shown to be helpful in treating various conditions including chronic pain, autoimmune disease, and even metabolic damage and weight loss resistance
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