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Malignant transformation of oral submucous fibrosis: a systematic review and meta-analysis
The current evidence base is heavily skewed towards preclinical studies, and while these provide a strong foundation, they cannot definitively predict human outcomes
It was shown to up- and down-regulate large groups of human genes, including many involved in nervous system development, maintenance, cell survival, and tissue repair, and may even reverse harmful age-related gene silencing
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