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Diagnostic methods such as GC/MS became more widely available in the 1980s and later so that the patients with IEMs were diagnosed with an IEM instead of Reyes syndrome
Benzyl alcohol can cross the placenta and is also likely excreted in breast milk in small amounts
Tesamorelin acetate administration to rats during organogenesis and lactation produced hydrocephaly in offspring at a dose of approximately two and four times the clinical dose, respectively, based on measured drug exposure (AUC)
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