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The Gsh1 and Gsh2 of conventional GSH biosynthetic pathway or the bifunctional GshF reported previously have been independently modulated for GSH production
By blocking NNMT, 5-amino-1MQ promotes an increase in nicotinamide adenine dinucleotide (NAD+), a cofactor essential for cellular metabolism
Through its modulation of the NNMT-SAM-NAD+ axis, it enhances energy expenditure and supports more efficient utilization of fat stores for energy, making it a strong candidate in studies exploring metabolic optimization and obesity control
Blood 88(10):199b, 1996
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